Vanilla is a product of Lussumo:Documentation and Support.
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Quick sketch in MangaStudio, upon I remembered that Oda IS circles; she is the essense of round. All of her distinguising features are derived from nice circles.
Cintiq too expensive? Wacom tablet is still awesome alternative.
And also, drawing with a mouse? VERY tough, although I almost killed myself when I found out that Adam Hughes does ALL his painterly coloring with a mouse!