This is just .... wow. A lit glurgy for Whitechapel but still:
Paolo Zamboni is an Italian surgeon.
When his wife developed Multiple Sclerosis, he decided to find a cure.
He knew he couldn't match the work being done by the large established research teams so he combed the literature looking for a new approach.
In very early papers on the disease he found hints that it might be linked to excessive iron building up in the brain - which was right up his street because he'd previously worked on treating a condition where iron accumulated in the legs and caused nerve damage.
So the MRIs' his wife, finds a blocked vein in her brain, gets permission to treat it with a simple catheterisation procedure - and three years later she's still completely asymptomatic.
So are almost 3/4s of the people in the first controlled test of the treatment.